The pathology of the gastrointestinal tract
Project Leader: Dr Richard Colling, Academic Clinical Fellow
Richard is interested in the pathology of the gastrointestinal tract, particularly colorectal carcinoma. He started work in this area in Oxford by collaborating on a number of translational, small projects which he has presented as posters at conferences both in the UK and abroad, and submitted as two papers for publication.
The focus of his lab work has now moved towards basic science. He is investigating the role of metabolism of colorectal carcinoma cell lines and its relation to angiogenesis. It is well established that hypoxia plays a strong role in the process of angiogenesis but he and the lab team think that glucose availability may play a part as well. Richard’s work so far has involved cell culture, assaying oxygen consumption, histology, immunohistochemistry and western blotting.