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Dual vector approaches in retinal gene therapy

How can the expression of dual adeno-associated virus (AAV) vectors being trialled in Stargardt’s inherited juvenile macular degeneration be optimised?

The pathogenesis of IgG4-Related Disease  

Investigating what characterises this newly-recognised, multi-organ, inflammatory disease, and what genes might be involved, and how.

High-fidelity simulation programmes for medical education

Developing simulations of surgical emergencies and on-call for the training of Foundation Year 1 doctors.

Strengthening capacity for antimicrobial stewardship in Vietnam

Addressing the issue of antibiotic resistance in a low-income country where limited resources constrain access to newer, more expensive drugs.


It is crucial that transfusion blood products are used carefully. Can electronic decision support systems be helpful? Could they lead to patients having blood products withheld inappropriately?