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Projects which our ACFs have done - often in preparation for a DPhil/PhD application.

 

GENERAL PRACTICE 

Understanding prognosis for patients with chronic heart failure

Information is needed to inform management decisions, advanced care planning, and public health and policy planning.   

MEDICAL ONCOLOGY

The genetics of inherited and sporadic colorectal cancer

Sequencing genes in a large cohort of individuals with cancer to identify carriers of genes implicated in cancer and characterise their phenotypes 

Paediatrics

HIV evolution in early infancy and mother to child transmission 

Looking at how the HIV virus evolves can provide evidence of the immune system acting on the virus to drive mutations 

PSYCHIATRY

Neurodegeneration in Altzheimer’s disease

Using a drosophilia model to look for therapies to treat and prevent Alzheimer’s disease 

RADIOLOGY

Hyperpolarised xenon magnetic resonance imaging 

Investigating the use of a novel non-radioactive gas contrast imaging technique

RESPIRATORY MEDICINE

Ultrasound markers of successful pleurodesis in malignant pleural effusion

Finding ultrasound markers that may allow clinicians to identify patients whose pleurodesis has been successful and can be discharged home earlier than currently 

SURGERY AND TRAUMA & ORTHOPEDICS 

Clinical outcome assessment in hand surgery

Assessing the validity, responsiveness and interpretability of existing patient-reported outcome measures, and understanding the impact of hand conditions and their treatment 

 

The role of absorbable nano-fibre scaffolds in treating chronic tendinopathy

Research into improving the way we treat patients with chronic tendon and ligament degenerative disease 

 

Investigating the potential translation of regulatory cellular therapies into paediatric surgical patients

A study which will analyse the frequency and function of Regulatory T Cells (Treg) in paediatric patients with T1DM compared to healthy children undergoing elective surgery